China (Mainland)
- Product Details
Keywords
- diosmin hesperidin
- Diosmin micro powder
- Diosmin CEP supplier
Quick Details
- ProName: Diosmin EP8
- CasNo: 520-27-4
- Molecular Formula: C28H32O15
- Appearance: greyish-yellow or light yellow hygrosc...
- Application: 520-27-4
- DeliveryTime: prompt delivery
- PackAge: 25kg/drum
- Port: China Mainport
- ProductionCapacity: 500 Metric Ton/Year
- Purity: 90-102%
- Storage: keep in cool and dried place
- Transportation: avoid damp and strong light
- LimitNum: 25 Kilogram
Superiority
We can offer normal powder and micopowder diosmin EP7 500tons per year.CEP and eDMF document is available. The price is competitive. If you are interesting,pls contact me.
Details
Specification of Diosmin Ph.Eur.7.0
|
Test Items |
Specification |
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CHARACTERS |
|
|
-Appearance |
Greyish-yellow or light yellow hygroscopic powder |
|
-Solubility |
Practically insoluble in water, soluble in dimethylsulphoxide, practically insoluble in alcohol. It dissolves in dilute solutions of alkali hydroxides. |
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IDENTIFICATION |
|
|
A.Infrared absorption spectrophotometry(2.2.24) |
Comparison: diosmin CRS |
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B.Examine the chromatograms obtained in the Assay |
The principal peak in the chromatogram obtained with the test solution is similar in retention time and size to the principal peak in the chromatogram obtained with reference solution (a). |
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TESTS |
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|
-Iodine(2.2.36)&(2.5.10) |
≤0.1% |
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-Related substances(HPLC)(2.2.29) |
|
|
--impurity A:acetoisovanillone |
≤1.0% |
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--impurity B:hesperidin |
≤5.0% |
|
--impurity C:isorhoifin |
≤3.0% |
|
--impurity E:linarin |
≤3.0% |
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--impurity F:diosmetin |
≤3.0% |
|
--any other impurity |
≤1.0% |
|
--total of other impurities and impurity A |
≤1.0% |
|
--total |
≤10.0% |
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-Heavy metals(2.4.8) |
≤20ppm |
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-Water(2.5.12) |
≤6.0% |
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-Sulphated ash(2.4.14) |
≤0.2% |
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ASSAY(HPLC),anhydrous substance(2.2.29) |
90.0%-102.0% |
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PARTTICLE SIZE |
95% pass 80mesh |
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RESIDUAL SOLVENTS(2.4.24)&(5.4) |
|
|
-Methanol |
≤3000ppm |
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-Ethanol |
≤5000ppm |
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-Pyridine |
≤200ppm |
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MICROBIOLOGICAL TESTS(2.6.12)&(2.6.13) |
|
|
-Total Plate Count |
＜1000/g |
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-Enterobacteriaceae count |
＜100/g |
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-Yeast and Molds |
＜100/g |
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-Salmonella |
Negative |
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-E.Coliform |
Negative |
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-Staphaureus |
Negative |
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-Ps.Aeroginosa |
Negative |
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STORAGE CONDITIONS/TEMPERATURE: ROOM TEMPERATURE, PROTECT FROM LIGHT, AIR TIGHT. |
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